Print This Page

Home Agriculture & Food Food Ingredients Other Accessary Foods

Weizmannia Coagulans -Heat Resistant Probiotics pictures & photos

Weizmannia Coagulans -Heat Resistant Probiotics pictures & photos

Weizmannia Coagulans -Heat Resistant Probiotics pictures & photos

Weizmannia Coagulans -Heat Resistant Probiotics pictures & photos

Weizmannia Coagulans -Heat Resistant Probiotics pictures & photos

Weizmannia Coagulans -Heat Resistant Probiotics pictures & photos

Weizmannia Coagulans -Heat Resistant Probiotics

Storage Method:	Frozen
Shelf Life:	>12 Months
Package:	1 Kg/Aluminum Foil Bag or on Requirements
Applications:	Fermented Products, Medication, Food Products
Benefits 1:	Improve Uremia
Benefits 2:	Improve Chronic Nephritis

Samples:	US$ 395/kg 1 kg(Min.Order) \| Request Sample

Customization:	Available \| Customized Request

Contact Supplier

Contact Now

Inquiry Basket

BioGrowing Co., Ltd.

Manufacturer/Factory & Trading Company

360° Virtual Tour

Diamond Member Since 2023

Suppliers with verified business licenses

Shanghai, China

Audited Supplier

High Repeat Buyers Choice

More than 50% of buyers repeatedly choose the supplier

Years of Export Experience

The export experience of the supplier is more than 10 years

Overseas Services

The supplier provides overseas services and supports countries including USA.

Overseas service content includes N/A.

Flexible Customization

The supplier provides Flexible customization services for your Personalized requirements

to see all verified strength labels (33)

Product Description

Company Info.

Overview
Product Description

Basic Info.

Model NO.

BC-G44

Benefits 3

Alleviate Gluten Allergy

Qualifications

FDA-GMP/QS, ISO 9001/22000, HACCP, NSF-cGMP

Transport Package

Aluminum Foil Bag

Specification

100 billion

Trademark

Flora-Focus

Origin

China

HS Code

3002493090

Production Capacity

600 Tones/ Year

Product Description

Weizmannia Coagulans -Heat Resistant Probiotics

Flora-Focus® Probiotic Powder
Weizmannia coagulans BC-G44

1. CHARACTERISTICS OF THE SPECIES

Weizmannia Coagulans is a lactic acid bacterial species, gram-positive, catalase positive, spore-forming, motile and a facultative anaerobe. Weizmannia is named in honor of Chaim Weizmann, a noted biochemist, who later became the first President of the State of Israel. Although its metabolism prefers mesophilic temperature

of about 40ºC, it can grow at temperatures from 30ºC to 55ºC; it grows in the pH range of 5.5 to 7.0.

2. SELECTION AND TAXONOMY

Weizmannia Coagulans BC-G44 is isolated from fermented Yellow Peach. Weizmannia Coagulans BC- G44 survival rate to show its application advantages in

various food and beverage categories. We know that formulation interactions and processing parameters have significant impacts on probiotic strain's stability.

Weizmannia Coagulans -Heat Resistant Probiotics

Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Bacillaceae
Genus: Weizmannia
Species: Weizmannia Coagulans
Strains:BC-G44

3. SAFE FOR CONSUMPTION
3.1 Safe Production
(1) Probiotics  strain  Weizmannia  Coagulans  by  the China Food and Drug Administration (CFDA) for use in food as a safe edible fungus.
(2) The production line  Weizmannia Coagulans BC- G44    is    completed    under    the    quality    system    of ISO/HACCP/NSF-cGMP/Kosher, etc
3.2 Non-GMO Declaration
(1) The strain has not been genetically modified.
(2) Within our controllable range, the raw materials, preservatives, and diluents  used  for  the production  of freeze-dried bacterial powder do not contain genetically
modified components.
3.3 Genetic identification and strain preservation
Weizmannia Coagulans BC-G44 is owned by Biogrowing Company.   This  strain has undergone  a  series of evaluations through the probiotic evaluation system and has been  identified  by  the  Institute  of Microbiology, Chinese Academy of Sciences, based on 16s-rRNA gene sequencing.  It belongs  to  the subspecies   Weizmannia Coagulans and is preserved in the China Center for Type Culture Collection with the accession number CCTCC.M.2018445.

4. HEALTH-RELATED PROPERTIES

General Probiotic Properties

Resistance to acid and bile salt

Items	Test Description	Performance
Gastro-Acid tolerance	The proportion of viable cell is 100% (can withstand 1 hour at pH 3.0 hydrochloric acid at 37ºC) The proportion of viable cell is	Excellent
Bile-Salt tolerance	≥ 80% (can withstand 1 hour at 37 ºC in 0.2% bile salt concentration)	Excellent

5. IN VIVO STUDIES
5.1 Boost Immunity (Zebrafish Test)
Randomly select transgenic macrophage green fluorescent line zebrafish at 5dpf in a 6-well plate, with 30 zebrafish treated in each well (experimental group). Water-soluble Weizmannia Coagulans BC-G44 (concentration as shown in Table 1) were administered, while normal control group and model control group were set up, with a volume of 3ml per well. Except for the normal control group, all other experimental groups were injected with Poly(I:C) to establish a zebrafish viral pneumonia model. After 3h of treatment at 28°C, 10 zebrafish from each experimental group were randomly selected and photographed under a fluorescent microscope. NIS Elements D 3.20 advanced image processing software was used to collect data, analyze the fluorescence intensity of macrophages at the site of zebrafish inflammation, and evaluate the immunomodulatory efficacy of the samples based on the statistical analysis results of this indicator. Statistical processing results were represented as mean ± SE. Statistical analysis was performed using SPSS 26.0 software, with P < 0.05 indicating statistical significance. Under the conditions of this experiment, Weizmannia Coagulans BC-G44 exhibits immunomodulatory efficacy, specifically manifested as a decrease in the fluorescence intensity of macrophages. Please refer to Figure 2 and
Figure 3 for details.

Table 1 Evaluation of the immunomodulatory efficacy of Weizmannia Coagulans BC-G44 coagulation. (n = 10)

Groups	Dose (μg/ml)	Fluorescence intensity of macrophages (pixels, mean ± SE)
Normal groups Model groups	- - 500	11348 ± 530 * 48811 ± 2145 37161 ± 900
BC-G44 groups	1000 2000	35453 ±634 *** 37794 ± 984*

Weizmannia Coagulans -Heat Resistant Probiotics

Figure 2 The fluorescence intensity of macrophages at the position of the swim bladder in zebrafish after treatment with Weizmannia Coagulans BC-G44 was compared with the model control group, * P < 0.05, ** P < 0.01, *** P < 0.001.

Weizmannia Coagulans -Heat Resistant Probiotics

Weizmannia Coagulans -Heat Resistant Probiotics

Figure 3. Fluorescence intensity of macrophages in the zebrafish swim bladder position.
The results show that under the experimental conditions, the  Weizmannia Coagulans  BC-G44 has immunomodulatory effects,  specifically manifested as a
decrease in the fluorescence intensity of macrophages.

5.2 Sport Nutrition (Zebrafish Test)

Randomly selected 3dpf wild-type AB strain zebrafish were placed    in    6-well    plates,    with    each    well (experimental group) treated with 30 zebrafish. The fish were  administered  a water-soluble dose  of Weizmannia Coagulans  BC-G44 (concentration  see  Table  2), while also  setting up  a  normal  control  group  and  a  model control group, with each well holding a volume of 3ml.  After treatment at 28°C for 96 hours (with fluid change at 48h), 10    zebrafish    were    randomly    selected    from    each experimental group, and their total movement distance within 1 hour was measured using a behavior analyzer. The statistical analysis results of this indicator were used to evaluate    the    exercise    nutritional     efficacy    of Weizmannia Coagulans BC-G44.  Statistical processing results are expressed as mean ±  SE. Statistical analysis was conducted using SPSS26.0 software, with P < 0.05 indicating statistically significant differences.
In  this experimental  condition,   the     condensed Weizmannia   Coagulans   BC-G44   has   the    effect   of promoting exercise  nutrition, specifically manifested as an increase in total distance traveled (Figure 4).

Table 2 BC-G44 Nutritional and Physical Activity Efficacy Evaluation Results. Compare with model control group ** P <0.01, ***P <0.001.

Groups	Dose (μg/ml)	Movement distance (mm, mean ± SE)
Normal groups Model groups	- - 31.2	2940 ± 234 ** 1964 ± 220 2493 ± 231
BC-G44 groups	62.5 125	2898 ± 185 3427 ± 209*

Weizmannia Coagulans -Heat Resistant Probiotics

Figure   4   The   total   distance   traveled   of   zebrafish   was compared   to    the   control   group,    with    **P<0.01    and
***P<0.001.

6. BENEFIT SUMMARY
Many scientific studies have supported the tremendous health-enhancing effects of Weizmannia Coagulans BC- G44 either  in  single  strain  form, in  combination  with other probiotics strains or as a component of synbiotics preparations, as shown above. Following is a summary of
these health benefits:
(1)   Gut-flora balance
(2)   Helps to build a superior immune system.
(3)   Boost immunity.
(4)   Enhanced the muscle's function.

7. APPLICATIONS

(1)   Medication,   HealthCare,  Dietary  Supplements,  in forms of capsules, tablet, sachets/strips, drops etc.
(2)   Food including gummies, hot drinks etc.
(3)   Animal nutrition products; Animal feed.
(4)   Animal feed starter cultures; Aquaculture feeds.

8. QUALIFICATION

(1)   FDA-GMP/QS
(2)   ISO 9001/22000
(3)   HACCP
(4)   HALAL
(5)   BRC GS
(6)   Kosher
(7)   NSF-cGMP
(8)   FSSC22000 certification
(9)   Health Canada NNHPD-FSRN
(10) National High-Tech Enterprise
(11) Contribution  to  China  government  for  industrial
standard/government standard for the probiotics.

9. INFERENCE

(1)   Hunter Biotechnology. Inc. Weizmannia Coagulans BC-G44  immunomodulatory  efficacy  test  report.
Project Number 5815. 2023. 3.24
(2)   Hunter Biotechnology. Inc. Weizmannia Coagulans BC-G44 Sport Nutrition test report. Project Number
5815. 2023. 3.24

Finally, let me introduce our company to you :

BioGrowing, headquartered in Shanghai, was founded in 2006. The production base covers an area of 36,666 square meters and has an annual capacity of 600 tons of highly active probiotics powder. It is one of the largest probiotics production bases in Asia. Its product range covers probiotic powder, starter cultures, functional food, and derivative products, widely used in food, medicine and healthcare, daily chemicals, agriculture, and many other fields.With "Reliable for a Better World" as its core value, BioGrowing is constantly committed to probiotics' research, development, and innovation, moving continuously towards the vision of a "global leading probiotics manufacturer" and providing customers with a full range of product solutions and quality services.
Please find attached our brochure so you can have a better idea of our products. You can check page 6 for single strains, pages 15-17 for a list of formulations developed by our R&D team.

Weizmannia Coagulans -Heat Resistant Probiotics

Weizmannia Coagulans -Heat Resistant Probiotics

Weizmannia Coagulans -Heat Resistant Probiotics

Weizmannia Coagulans -Heat Resistant Probiotics

Weizmannia Coagulans -Heat Resistant Probiotics

Weizmannia Coagulans -Heat Resistant Probiotics

Send your message to this supplier

*From:

*To:

*Message:

Enter between 20 to 4,000 characters.

This is not what you are looking for?  Post a Sourcing Request Now

Find Similar Products By Category

Supplier Homepage Products Probiotic strains Weizmannia Coagulans -Heat Resistant Probiotics

Hot Searches

Probiotics bulkbuy

You Might Also Like

Product Groups

Product Catalogs

Contact Supplier

Contact Now

Inquiry Basket

BioGrowing Co., Ltd.

360° Virtual Tour

Diamond Member Since 2023

Suppliers with verified business licenses

Audited Supplier

Manufacturer/Factory & Trading Company

Number of Employees

203

Year of Establishment

2006-09-22