| Varieties: | Parasite Disease Prevention Medicine |
|---|---|
| Component: | Animal |
| Type: | The First Class |
| Pharmacodynamic Influential Factors: | Animal Species |
| Storage Method: | Prevent High or LowTemperature |
| Veterinary Reg. No.: | 09853 |
| Samples: |
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| Customization: |
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Product name: Moxifloxacin hydrochloride
Other name: AVALOX;BAY-12-8039;Moxifloxacin hydrochloride Solution, 1000ppm;Moxifloxacin and intermediates;Moxifloxacin HCl (Monohydrate);(1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;Moxifloxacin HCl USP;1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
CAS: 186826-86-8
MF: C21H25ClFN3O4
MW: 437.8923032
EINECS: 641-756-7
Melting point: 324-325 °C
Storage Temp.: 2-8°C
Usage: Antibacterial
Description:
Moxifioxacin hydrochlodde is one of the two new fluoroquinolonecarboxylic acid antibiotics introduced in 1999 for the treatment of respiratory tract infections such as community-acquired pneumonia, acute exacerbations of bronchitis or acute sinusitis. Moxifloxacin can be synthesized through a 12 step sequence from the classical 4-quinolone-3-carboxylic acid template. Some advantages of Moxifloxacin over Ciprofloxacin, another of Bayer's launched quinolones, have been shown, i.e. an enhanced activity against Gram-positive bacteria (Streptococcus pneumoniae, Clostndium pneumoniae), a favorable pharmacokinetic profile (good tissue penetration and plasma concentrations above MICs) and a lack of phototoxicity (UVA irradiation).
Usage:
Moxifloxacin Hydrochloride is a fluoroquinolone antibiotic developed by Bayer Pharmaceuticals (Germany.) It can be used to treat community-acquired pneumonia caused by Staphylococcus aureus, baccilus, pneumococcus, mucositis Moraxella, and Klebsiella pneumoniae, acute chronic bronchitis attacks, and acute sinusitis. For the treatment of adult bacterial lung infections, paranasal sinus, skin, and abdominal cavity. Also used to treat community-acquired pneumonia, chronic bronchitis, urogenital infection, and acute sinusitis.
Moxifloxacin is a kind of near white crystal powder chemical. Its molecular formula is C21H24FN3O4. Its molecular weight is 401.4314. Its melting point is 193-195 C. It is insoluble in water, slightly soluble in ethanol and almost insoluble in acetone. Moxifloxacin is a quinolone drug. It is mainly used to treat adults with upper and lower respiratory tract infections (> 18 years old), such as acute sinusitis, acute attack of chronic bronchitis, community acquired pneumonia, skin and soft tissue infections.
Moxifloxacin can be used to treat social acquired pneumonia caused by Staphylococcus aureus, influenza bacilli, pneumococcus, acute attack of chronic bronchitis, acute sinusitis, etc. It belongs to the fourth generation of quinolone antibiotics and is a new generation of broad spectrum antibiotics. It has strong antimicrobial activity against common respiratory pathogens such as Streptococcus pneumoniae, Haemophilus, Morahan catarrhalis and some Staphylococcus aureus, especially Streptococcus pneumoniae. It is clinically used to treat acute sinus adenitis, acute exacerbation of chronic bronchitis) community acquired pneumonia, as well as non-complications of skin and soft tissue
Moxifloxacin hydrochloride Specification:
| Analysis Test | Specification | Result |
| Description | crystalline powder | Conforms |
| Solubility | soluble in water | Conforms |
| PH | 6.0~7.5 | 6.9 |
| Solution clarity and color | solution should be clear and colorless | Conforms |
| Related substances | 5'CMP 0.3% Simple impurity Total other impurity |
0.01% 0.03% 0.10% |
| Chloride | 0.05% | Conforms |
| Ammonium | 0.05% | Conforms |
| Fe | 0.01% | Conforms |
| Phosphate | 0.1% | Conforms |
| Loss on drying | ≤6.0% | 1.3% |
| Heavy metals | 0.002% | Conforms |
| Arsenide | 0.0001% | Conforms |
| Bacterial Endotoxins | 0.3EU/mg | Conforms |
| Microbial Limit | Conforms | Conforms |
| Assay(on dried basis) | ≥98.0% | 98.8% |
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