Supply High Quality Pharmaceutical Raw Materials Estrogen Estradiol Benzoate CAS No. 50-50-0

Function:
Estradiol benzoate is mainly used to supplement estrogen deficiency, such as atrophic vaginitis, vaginal dryness, female gonadal dysfunction, vulvar dryness, menopausal vasomotor symptoms, ovariectomy, primary ovarian failure, etc. Amenorrhea, menopausal syndrome, withdrawal of milk and prostate cancer, etc. 

Application:
Estradiol benzoate is an estrogenic drug. The same effect as estradiol, can make endometrial hyperplasia, enhance contraction of uterine smooth muscle, promote breast growth and proliferation: large doses of prolactin inhibition, anti-androgen effect, and increase calcium deposition in bone. This product is mainly metabolized in the liver, which is decomposed into estradiol, and partially binds to sex hormone binding globulin (SHBG). The unconjugated free part binds to the target tissue and estrogen receptor, which produces estrogenic effect through transcription and protein synthesis. In the liver or kidney, estrogen binds to glucuronic acid or sulfuric acid and becomes a water-soluble salt which is quickly discharged from the kidney.

Uses:
Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.
Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.


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A6  Different quantity has different discount.
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