| CAS No.: | 164650-44-6 |
|---|---|
| Formula: | C18h22f2n4o |
| EINECS: | 813-597-5 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
|---|
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier Puya Supply KP 103 / Efinaconazole CAS 164650-44-6 Treatment Of leuconychia
Product Name: KP 103
Synonyms: 1-Piperidineethanol, α-(2,4-difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βR)-;JUBLIA; KP 103; KP103;Efinaconazole (Jublia);KP 103;Efinaconazole;(alphaR,betaR)-alpha-(2,4-Difluorophenyl)-beta-methyl-4-methylene-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol;KP 103 (pharmaceutical);Jublia
CAS: 164650-44-6
MF: C18H22F2N4O
MW: 348.39
EINECS: 813-597-5
Product Categories: Inhibitors
Mol File: 164650-44-6.mol
Efinaconazole is a broad-spectrum triazole antifungal agent with activity against Acremonium, Aspergillus, Candida, Cryptococcus, Epidermophyton, Fusarium, Microsporum, Paecilomyces, Pseudallescheria, Scopulariopsis, Trichophyton, and Trichosporon. It inhibits the growth of T. rubrum and T. mentagrophytes clinical isolates with MIC values ranging from ≤2.0 to 60 ng/ml and of C. albicans isolates with MIC values ranging from ≤0.5 to >250 ng/ml. Efinaconazole inhibits sterol 14α-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. It inhibits ergosterol biosynthesis in T. mentagrophytes and C. albicans with IC50 values of 7.0 and 0.40 ng/ml, respectfully. Topical formulations containing efinaconazole have been used for the treatment of onychomycosis.
KP 103 / Efinaconazole CAS 164650-44-6 of Chemical Properties
Melting point 107-108 °C
Boiling point 473.3±45.0 °C(Predicted)
density 1.08±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Chloro form (Sparingly), DMSO (Slightly), Ethyl Ace tate (Slightly), Methan ol (Sli
form Solid
pka 7.7 (25°); 6.6 (70°)
color Off-White to Pale Beige
CAS DataBase Reference 196618
EPA Substance Registry System 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R,4R,5S)- (196618-
Efinaconazole (CAS 164650-44-6) is a synthetic antifungal agent that is used for the treatment of onychomycosis, a fungal infection that affects the nails. It is a topical solution that is applied to the affected nails and surrounding skin.
Function: Efinaconazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption weakens the membrane and leads to the death of the fungal cells.
Application: Efinaconazole is used to treat onychomycosis, a fungal infection that affects the toenails and fingernails. It is effective against a wide range of fungi, including dermatophytes, yeasts, and molds. It is available in the form of a topical solution, which is applied to the affected nails and surrounding skin once a day. The treatment course usually lasts for 48 weeks for toenail infections and 12 weeks for fingernail infections.
| Shipping Terms | ||
| By Express | By Air | By Sea |
| Suitable for under 50kg Fast:3-4 days High cost Door to door service Easy to pick up the goods |
Suitable for more than 50kg Fast:3-4 days High cost Airport to airport Professional broker needed |
Suitable for more than 500kg Slow:15-30 days Low cost Port to port Professional broker needed |
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
FAQ
Q1. What's the MOQ?
A: Usually 1 kg. It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.
Suppliers with verified business licenses
Audited Supplier 
){kind=link}
){kind=link}