Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale

CAS No.: 1369773-39-6
Formula: C48h56can2o10
Environmental Protection: Yes
Certification: ISO, SGS
Color: White
Classification: Supplement
Customization:
Manufacturer/Factory, Trading Company
Gold Member Since 2018

Suppliers with verified business licenses

Shaanxi, China
to see all verified strength labels (9)

Basic Info.

Model NO.
1369773-39-6
Function
Keeping Health and Promoting Growth
Appearance
Powder
Item
Ahu-377 (Sacubitril) Lcz696 Intermediate
Transport Package
Foil Bag/Drum/as Per Your Request
Specification
99%
Trademark
IKNOW
Origin
China
Production Capacity
500kg/Per Month

Product Description

Pharmaceutical Raw Material AHU-377 (Sacubitril) LCZ696 Intermediate White Powder For Sale

Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale
Product Description----------------------------------------------------------------------------------------------------------


AHU-377 (Sacubitril) is a prodrug which is activated in vivo by hydrolytic enzyme esterases to form an active compound LBQ657 that selectively and potently inhibits the enzyme Neprilysin with Ki at low nM. Neprilysin is a protease responsible for the degradation of atrial and brain natriuretic peptides. Inhibition of the enzyme prevents the degradation of natriuretic peptides and activates cGMP signaling pathways that regulate volume and blood pressure. AHU-377 (Sacubitril) is an investigational antihypertensive drug being studied for use in combination with Valsartan (molar ratio: 1:1) (Our Prod No. CT-VALS). The combination drug, known as LCZ696, is in clinical trials for the treatment of heart failure.

Detailed Information

Basic Information

 
Product Name AHU-377 (Sacubitril)
Purity 99%
Synonyms Ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoate hemicalcium salt;LCZ696(valsartan + sacubitril) impurity 1;(alphar;1'-biphenyl]-4-pentanoic acid 4-ethyl ester calcium salt (2:1);gammas)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1;Sacubitril Hemicalcium salt;(αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester calcium salt;Sacubitril Calcium
CAS 1369773-39-6
MF C48H56CaN2O10
MW 861.04364
Product Categories -;Intermediates;lcz696;LCZ 696;Pharmaceutical Intermediates
Mol File 1369773-39-6.mol

Chemical Properties
 
Storae temp. -20ºC
Form Powder
color White powder

Application

LCZ696 Intermediate

Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale
Packing & Shipment

Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale


Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for SalePharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
detailed Certificate of Analysis.

3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
pharmaceutical and/or food standards.

5) Warehousing and storage: Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.

Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale

Certification

Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale


Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale

Pharmaceutical Raw Material Ahu-377 (Sacubitril) Lcz696 Intermediate CAS 1369773-39-6 White Powder for Sale
 
Q1:Which kind of payment terms do you accept?
For small order,you can pay by T/T or Western Union ,nomal order by T/T to our company account.

Q2:Can you give me a discount price?
Surely,It depend on your quantity.

Q3:How can I get a sample?
Free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. 

Q4: How to confirm the Product Quality before placing orders?
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. 

Q5:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Send your message to this supplier

*From:
*To:
*Message:

Enter between 20 to 4,000 characters.

This is not what you are looking for? Post a Sourcing Request Now

You Might Also Like

Gold Member Since 2018

Suppliers with verified business licenses

Manufacturer/Factory, Trading Company
Registered Capital
3000000 RMB
Plant Area
501~1000 square meters