Pharmaceutical Intermediates Tiotropium Bromide Monohydrate CAS 139404-48-1

1. Bronchodilation: The primary function of Tiotropium Bromide Monohydrate is bronchodilation, which refers to the relaxation of the smooth muscles lining the airways in the lungs. By binding to specific receptors (muscarinic receptors) in the airway smooth muscles, Tiotropium inhibits the action of acetylcholine, a neurotransmitter involved in bronchoconstriction. This results in the relaxation of the airway muscles and dilation of the airways, promoting improved airflow and reducing respiratory symptoms.

2. Long-acting Effects: Tiotropium Bromide Monohydrate is classified as a long-acting bronchodilator due to its prolonged duration of action. It provides 24-hour bronchodilation, allowing for once-daily dosing. This sustained effect helps to maintain improved lung function and symptom control throughout the day, offering convenience and enhanced treatment adherence for patients.

Treatment of COPD Tiotropium Bromide Monohydrate is primarily used in the treatment of chronic obstructive pulmonary disease (COPD), a chronic inflammatory lung disease characterized by airflow limitation. It helps to relieve symptoms, improve lung function, and reduce exacerbations in patients with COPD. Tiotropium is usually administered via inhalation, providing targeted delivery directly to the lungs.