CAS No.: | 10314-98-4 |
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Formula: | C14h17no4 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Technical |
Colour: | White |
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N-CBZ-piperidine-4-carboxylic acid is widely used as a protecting group in organic synthesis. Its function is to temporarily block the reactivity of specific functional groups during chemical reactions. In the case of N-CBZ-piperidine-4-carboxylic acid, the carbobenzoxy (CBZ) group is attached to the piperidine nitrogen, forming a stable and inert derivative. This allows selective reactions to be performed on other parts of the molecule without affecting the CBZ-protected piperidine group.
The primary application of N-CBZ-piperidine-4-carboxylic acid lies in the synthesis of pharmaceutical compounds. By temporarily protecting the piperidine nitrogen, chemists can perform reactions on other functional groups while maintaining the structural integrity of the piperidine ring. Once the desired modifications are complete, the CBZ group can be easily removed, revealing the free piperidine amine.
This compound has found application in the synthesis of various drugs, including antipsychotics, antidepressants, and analgesics. It is often employed in the preparation of piperidine-containing building blocks, which are crucial in pharmaceutical research and development.
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