Pharmaceutical Intermediates Ethyl-N-Boc-Piperidine-3-Carboxylate CAS 130250-54-3

Ethyl-N-BOC-piperidine-3-carboxylate is a chemical compound that belongs to the class of piperidine derivatives. It is widely used in pharmaceutical and chemical research due to its unique structure and versatile properties. This compound is derived from piperidine, a cyclic amine, by esterification with ethyl alcohol and protection of the amine group with the BOC (tert-butoxycarbonyl) protecting group.

The BOC protecting group plays a crucial role in organic synthesis, particularly in the protection of the amine functionality. By temporarily masking the amine group, the BOC group prevents undesired reactions or unwanted side reactions during subsequent chemical reactions. It can be selectively removed under specific conditions to reveal the free amine group, allowing for further functional group manipulation or chemical transformations.

1. Pharmaceutical Synthesis: Ethyl-N-BOC-piperidine-3-carboxylate serves as a valuable building block in the synthesis of various pharmaceutical compounds. The BOC-protected piperidine moiety can be selectively deprotected, followed by further functionalization to introduce specific chemical groups or substituents. This compound has found applications in the synthesis of drugs targeting central nervous system disorders, cardiovascular diseases, and other therapeutic areas.

2. Chemical Research: Ethyl-N-BOC-piperidine-3-carboxylate is widely used as a versatile intermediate in chemical research and development. It provides flexibility in the synthesis of complex organic molecules, including natural products, pharmaceuticals, and advanced chemical building blocks. The BOC protection strategy allows for precise control over the reactivity and selectivity of the piperidine moiety during subsequent reactions.