What's Cefotaxime Sodium?
Cefotaxime sodium is a third-generation semi-synthetic cephalosporin, which is not as effective as cefazolin on gram-positive bacteria. Enterococcus is resistant to this product, is ineffective against penicillin-resistant pneumococcus, and has strong bactericidal activity against gram-negative bacteria. It has stronger antibacterial effect on Escherichia coli, influenzae bacillus, pneumoniae sensitive.
Cefotaxime is widely distributed in various tissues and body fluids throughout the body. The drug concentration in normal cerebrospinal fluid is very low; after applying this product in patients with meningitis, the effective concentration in cerebrospinal fluid can be reached. Effective concentrations can also be reached in bronchial secretions, middle ear discharge, pleural effusion, empyema pus, ascites, gallbladder wall, bile, and bone tissue: this product can enter the human fetal blood circulation through the placental barrier, and a small amount is also acceptable Into the breast milk.
Application & Function of Cefotaxime Sodium
Treatment of infections of lower respiratory tract including pneumonia, urinary tract, skin and skin structures, bone and joints; treatment of bacteremia/septicemia, CNS infections, intra-abdominal infections including peritonitis, gynecological infections including pelvic inflammatory disease, endometritis and pelvic cellulitis caused by susceptible strains of specific microorganisms; perioperative prophylaxis.
Function of Raw material Cefotaxime Sodium
The main clinical infection for susceptible strains of meningitis, pneumonia, skin and soft tissue infections, peritonitis, urinary tract infections, gonorrhea, liver and gallbladder infection, surgical trauma, sepsis, and genital infections. As a treatment for gonorrhea has been first-line drugs
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