| CAS No.: | 155206-00-1 |
|---|---|
| Formula: | C25h37no4 |
| EINECS: | 642-890-9 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Customization: |
|---|
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Audited Supplier Product name |
Bimatoprost |
| CAS Number | 155206-00-1 |
| Appearance | white powder |
| Molecular Weight | 528.53g/mol |
| Molecular Formula | C25H37NO4 |
| Sample | provide |
| Packing | Stealth packaging or as required |
KANAL Bimatoprostused topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes.
Application
1.KANAL Bimatoprost is a class of high-performance antihypertensive drugs, it is unique in pharmacology, is a synthetic prostaglandin amide,has a strong role in lowering intraocular pressure.
2.KANAL Bimatoprost may be through the hydrolysis of free acid after the role of FP class prostaglandin receptor, so the treatment of glaucoma than horse prostaglandin commonly used concentration of 0.03%.
Specification
| Item | Specifications | Results |
| Appearance | White powder | White powder |
| Identification(byHPLC) | RT of the sample should match with stand in the Related substances | Complies |
| Solubility | Very soluble in ethanol, m'ethanol, slightly soluble in water | Complies |
| Water | NMT 0.5% | 0.43% |
| Purity | NLT 99.0% | 99.88% |
| Specific rotation | Between + 33º to +37º | 36.80% |
| Residue on ignition | NMT 0.1% | 0.02% |
| Heavy metals | NMT 10ppm | Complies |
| 15β-bimatoprost | NMT 0.2% | Not detected |
| Total other impurities | NMT 0.5% | 0.08% |
| Ethanol | NMT 0.5% | Not detected |
| Ethyl-acetate | NMT 0.5% | 0.10% |
| nHexane | NMT 0.29% | Not detected |
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