Nucleoside drugs CAS 51-21-8 5-Fluorouracil
| Product name |
5-Fluorouracil |
| Cas No. |
51-21-8 |
| Molecular Formula |
C4H3FN2O2 |
| Appearance |
White crystalline powder |
5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.
Application & Function of 5-Fluorouracil
1. Fluorouracil is used for biochemical studies and antitumor drugs.
2. Fluorouracil is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.
3. Fluorouracil is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.
4. Antimetabolite antitumor drugs.
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