• Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan
  • Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan
  • Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan
  • Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan
  • Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan
  • Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan

Marine Materials for Surgery Absorbable Hemostasis Surgical Fabric Carboxymethyl Chitosan

Certification: ISO, CE
Feature: Anti-Allergy, Antibacteria
Type: Biologically Active Dressing
Composition: Chitosan
Advantages: Naturally Anti-Bacterial Promoting Healing
Certificate: ISO13485
Samples:
US$ 100/Piece 1 Piece(Min.Order)
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Customization:
Manufacturer/Factory, Group Corporation
Gold Member Since 2021

Suppliers with verified business licenses

Anhui, China
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Basic Info.

Model NO.
Hemostasis Surgical Fabric Carboxymethyl Chitosan
Use
Spinning, Non-Woven Fabric
Utility
Strengthening Immunity Adsorption Protection
Transport Package
Suit for The Exporting Packaging
Specification
20*20mm to 50*100mm
Trademark
yaliya
Origin
China
Production Capacity
50mt/Month

Product Description


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Key attributes

Other attributes

Place of Origin
China
Brand Name
YALIYA
Model Number
Hemostatic & Healing gauze
Disinfecting Type
Sterile
Size
other
Stock
Yes
Shelf Life
3 years
Material
CM-Chitosan
Quality Certification
CE
Instrument classification
Class III
Safety standard
Other
Properties
Hemostatic & Healing, recovery
material
Carboxymethyl Chitosan
colour
white
shape
fabric
MOQ
1000


Products Description
Chitosan based Wound Dressing is CE marked Class III product.
It is applicable for surgeries, nursing cares of different acute and chronic wounds (skin wounds and mucosal wounds), and it rapidly absorbs blood and wound exudates with functions of haemostasis and accelerating recovery of wounds.
Used for:surgical incisions, pressure ulcers, oral ulcers and painful wounds, etc.

Features:
+Stop bleeding during surgeries
+Absorb blood and wound exudates, form into gel
+Reduce operation time by quick hemostasis
+Accelerate would healing and recovery time
+Restrain the forming of scars
+Effective & Affordable
+Ease of Application & Painless Removal


[Mechanism of Action]
1. Mechanism of haemostasis
After contacting the blood and exudate of the wound, this Product partially forms the sticky gel which adheres to and blocks the wound for rapid haemostasis.
2. Mechanism of wound healing
The ingredient of this Product is chitosan derivative which is a polysaccharide with a similar molecular structure to the natural ECM and is prominent in biocompatibility. It has good properties of liquid absorbency and moisturization. This Product is transformed to a soft gel upon absorbing liquid to provide wounds with a moisturizing and simulating ideal healing environment of ECM, and to improve the comfort level of the wounds, relieve pains, facilitate wound repair and healing, and improve the quality of wound recovery.

Chitosan Hemostatic Agent Granule Powder for rapid hemostasis Absorbable Soluble medical hemostats dressing
1

Product descriptions from the supplier

This product has acquired the relevant product qualification(s)/license(s) of certain applicable country/countries.
Overview


Biotemed™ was founded in 2006, is a national high-tech enterprise applying proprietary biomedical technology for R&D, manufacturing and sales of biomaterials and medical devices. The company strategically target the fast-growing therapeutic areas, including hemostasis, surgical care, wound care and tissue engineering.

01.Anti-adhesion
03.Analgesia
05.Antibacterial
02.Fast hemostasis
04.Promotes healing
06.Biodegradable



A highly viscoelastic colloid is formed on the surgical wound to form a physical barri er with normal tissues and effectively prevent adhesions.

Effectively stop bleeding, reduce hematoma organization and fibroblast invasion, play a role in preventing adhesions.


Hemostasis in 5 seconds and effectively reducing bleeding volume in surgery. Doesn't rely on the body's own blood clotting system. 

The raw material is Alaska deep sea snow crab. Neutral pH and fully degrades in vivo without any residue in 7-14 days and the degradation products are oligosacchar and glucosamine,etc.


A variety of specifications to adapt to a variety of surgical blades.

Chitosan - based absorbable hemostatic nonwoven fabric
Main component: Carboxymethyl chitosan
Characteristics: White or light yellow nonwoven, uniform, soft, absorbable hemostatic material, sterile
Scope of application: It is used to control bleeding in capillaries, veins and arterioles during surgery when ligation or other conventional methods are not applicable or ineffective.
Size:20mm*20mm-50mm*100mm or etc.
Five functions:1, Rapid hemostasis 2, Prevent adhesion 3,Promote healing 4,Effective bacteriostasis 5,absorbable

Prevent adhesion:
(1) High viscoelastic colloid is formed on the surgical wound to form a physical barri er between it and normal tissue to effectively prevent adhesion;
(2) Effective hemostasis, reduce hematoma mechanization and fibroblast invasion, play a role in preventing adhesion.

Effective bacteriostasis:
Carboxymethyl chitosan inhibits metabolism and reproduction by changing the permeability of microbial cell membrane and entering the internal flocculating organelles.

Rapid hemostasis

(1) The high viscoelastic gel network structure can effectively physically seal the broken end of blood vessels;
(2) The effect of electric charge can activate the aggregation of blood cells, can adhere to platelets, and promote coagulation factors to initiate coagulation.

Promote healing
Carboxymethyl chitosan can promote the growth of normal fibroblasts.

Completely degradable
Complete degradation in 7-10 days


Effect 1: Quick hemostasis
Physical aggregation: After contact with blood, the non-woven form is transformed into a high viscoelastic gel, which is closely attached to the wound and effectively physically occludes the bleeding wound to achieve rapid hemostasis.
Charge aggregation: Chitosan cation aggregates red blood cells through charge, adheres to platelets, promotes the release of coagulation factors, and thus stops bleeding.

Aggregation of red blood cells in vitro.
The component of the yarn, carboxymethyl chitosan, is the only positively charged substance in the biological material, which can trap red blood cells to aggregate and form blood clots.

An open wound (5mmx3mmx2mm) was created in the left lobe of the rat liver to form a bleeding model. The experimental group applied Zhuyi yarn to the wound, and the control group applied yarn as quickly as possible. The hemostatic time and total blood loss (TBL) were recorded.
The experimental results showed that the hemostasis time of the experimental group was shorter than that of the control group, and the TBL was also smaller.

Efficacy 2: Prevent adhesion
Carboxymethyl chitosan did not increase the collagen secretion level of fibroblasts.
At 24h and 48h, different concentrations of L-CMC did not increase the secretion of hydroxyproline from fibroblasts.
Within 72h, 100μg/ml L-CMC did not increase hydroxyproline secretion.
Carboxymethyl chitosan significantly increased the value of matrix metalloproteinase 1 (MMP-1).

The effect of anti-adhesion in SD rats was evaluated by anatomy in a 1cm*2cm abrasions model of the abdominal wall in the middle and lower abdomen.
The high adhesion ratio of carboxymethyl chitosan group was lower than that of other groups, indicating better ability to prevent postoperative adhesion.

Effect 3: Effective bacteriostasis
Carboxymethyl chitosan in high concentration can inhibit many kinds of bacteria.
Bacteriostatic results of carboxymethyl chitosan of different concentrations with molecular weight 6.6*104.
Bacteriostatic results of carboxymethyl chitosan with different concentrations of molecular weight 0.5*104.

Effect 4: significant analgesia
Carboxymethyl chitosan can inhibit the production of inflammatory factors in the blood

Effects of chitosan and carboxymethyl chitosan on the content of vascular soothing kinin in rat scald model

Effects of chitosan and carboxymethyl chitosan on the content of 5-hydroxytryptamine in blood of rat scalded model

Effect five: degradable absorption
Carboxymethyl chitosan degradation products are safe and non-toxic.
In the in vivo degradation and absorption test, the inflammation of Zhuyisha ® after 2 weeks implantation was grade 0, and the sample degradation was complete, which met the relevant requirements.

Usage and precautions
Usage method
1. Aseptic packaging, open the inner packaging can be used;
2. This product can be bent and cut into different shapes at will, suitable for irregular tissue wounds;
3. After the bleeding wound is clear, put this product on the bleeding wound and apply the gauze closely to the wound;
4. The bleeding wound does not need to be clean, it can be directly covered.

Matters needing attention
1. Should be strictly aseptic operation, do not use when the package is damaged;
2. Intraspinal indentation is not recommended during spinal surgery.
3. For orthopedic surgery, the bone marrow cavity should be avoided and not in contact with bone cement;
4. When using this product under endoscope, keep the instrument dry, roll the yarn into a roll and send it into the body cavity through Chowka.

 

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Gold Member Since 2021

Suppliers with verified business licenses

Manufacturer/Factory, Group Corporation
Registered Capital
10000000 RMB
Management System Certification
ISO 9001, ISO 14001, ISO 14000, ISO 14064, GMP, BSCI, ISO 13485, FSC