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Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin pictures & photos

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin pictures & photos

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin pictures & photos

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin pictures & photos

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin pictures & photos

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin pictures & photos

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

CAS No.:	75330-75-5
Formula:	C24h36o5
EINECS:	616-212-7
Type:	Synthesis Material Intermediates
Appearance:	White Powder
Quality:	Industrial

Samples:	US$ 1/gram 1 gram(Min.Order) \| Request Sample

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Guangzhou Tongyi Biochemistry Technology Co., Ltd.

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Product Description

Company Info.

Basic Info.

Model NO.

TY-79XQ

Colour

White

Package

Foil Bag

Place

China

Assay

99%

Shelf

2 Years

Transport Package

25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg

Specification

25kg/drum

Trademark

tongyon

Origin

China

Production Capacity

5000kg/Month

Product Description

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Product name	Lovastatin
CAS	75330-75-5
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Lovastatin
Product Name Lovastatin

CAS 75330-75-5

MF C24H36O5

MW 404.54

EINECS 616-212-7

MOL File 75330-75-5.mol

Chemical Properties

Melting point 175°C
alpha D25 +323° (c = 0.5 g in 100 ml acetonitrilie)
Boiling point 559.2±50.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
refractive index 320 ° (C=0.5, CH3CN)
storage temp. -20°C
solubility ethanol: soluble9.80-10.20mg/mL, clear, colorless to faintly yellow
form White to off-white powder
pka 13.49±0.40(Predicted)
Water Solubility 0.0004 mg/mL at 25 ºC
Merck 14,5586
CAS DataBase Reference 75330-75-5(CAS DataBase Reference)
EPA Substance Registry System Lovastatin (75330-75-5)

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Usage And Synthesis
a cholesterol lowering agent

Lovastatin is a cholesterol lowering agent isolated from a strain of Aspergillus terreus.
Lovastatin is a white, nonhygroscopic crystalline powder that is insoluble in water and sparingly soluble in ethanol, methanoil, and acetonitrilie.
After oral ingestion, lovastatin, which is an inactive lactone, is hydrolyzed to the corresponding β-hydroxyacid form. This is a principal metabolite and an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate limiting step in the biosynthesis of cholesterol.

General description

Lovastatin is a hexahydro naphthalenie ester isolated from Aspergillus terreus broth. It is an inactive lactone only yielding activity upon hydrolysis after oral administration. It has a strong competitive inhibition on the HMG-CoA reductase in the liver. HMG-CoA reductase is rate-limiting enzyme for de novo cholesterol synthesis in vivo. The inhibition of the enzyme can block the conversion of HMG-CoA to methacryliic acid, causing significant reduction in cholesterol synthesis, and leading to increased expression of the liver LDL receptor which promotes the plasma LDL-C clearance. The reduction of cholesterol synthesis can also cause reduced synthesis of liver ApoB100, thus causing that reduction of VLDL synthesis. Clinical observations show that it has a good effect of lowering of plasma total cholesterol and LDLC on hypercholesterolemia caused by various kinds of reasons such as heterozygous familial hypercholesterolemia, polygenic hypercholesterolemia, and diabetes or kidney disease syndrome.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

Manufacturer Supply High Quality CAS 75330-75-5 Lovastatin

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Guangzhou Tongyi Biochemistry Technology Co., Ltd.

Diamond Member Since 2021

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Audited Supplier

Trading Company

Number of Employees

2

Year of Establishment

2017-08-08