• Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
  • Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
  • Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
  • Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
  • Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
  • Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol

Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol

CAS No.: 3483-12-3
Formula: C4h10o2s2
EINECS: 222-468-7
Type: Synthesis Material Intermediates
Appearance: White Powder
Quality: Industrial
Samples:
US$ 1/gram 1 gram(Min.Order)
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Basic Info.

Model NO.
TY-02ALI
Colour
White
Package
Foil Bag
Place
China
Assay
99%
Shelf
2 Years
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month

Product Description

Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol

Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
 
Product name DL-Dithiothreitol
CAS 3483-12-3
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
DL-Dithiothreitol
Product Name DL-Dithiothreitol

CAS 3483-12-3

MF C4H10O2S2

MW 154.25

EINECS  222-468-7

MOL File3483-12-3.mol     Melting point 41-44 °C(lit.)
alpha  -0.2~+0.2°(20ºC/D)(c=5,H2O)
Boiling point 125 °C
Density  1.04 g/mL at 20 °C
vapor density  5.3 (vs air)
refractive index  1.5200 (estimate)
Flash point >230 °F
storage temp.  2-8°C
solubility  H2O: 50 mg/mL, clear, colorless
pka pK1:8.9 (25°C)
form  Powder
color  White
Odor Unpleasant Odor


Manufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol
Usage And Synthesis
Common reductant

DL-1, 4-DL-1, 4-Dithiothreitol is a common reducing agent, also known as DTT with a strong reduction capability. Its reduction capability is largely due to the conformational stability of the six-membered ring (containing disulfide bone) of its oxidation state. The reducing capability is affected by the pH value and also takes effect only in the case of a pH being greater than 7. This is because it is only the deprotonated thiolate anion (-S-) that is actively in reduction reaction while thiol (an-SH) is not; and the pKa of mercapto group is typically around~8.3.
The reduction of the disulfide bond mediated by DL-1, 4-Dithiothreitol mainly consists of a two-step continuous sulfhydryl-disulfide exchange: wherein the intermediate state formed by the first step of the reaction is very unstable because the secondary sulfhydryl group of DTT tends to connected by the oxidized sulfur atom, making the intermediate state be rapidly converted to the cyclic oxidation structure of DTT, thus completing the reduction of disulfide bonds.
Since being easily oxidized by air, the stability of DL-1, 4-Dithiothreitol (DTT) is relatively poor; frozen storage or processing in inert gas can extend its duration life. Owing to the low nucleophilicity of the protonated sulfur, with the decreased pH value, the effective reducing capability of DTT is also reduced; Moreover, Tris (2-carboxyethyl) phosphinee HCl (TCEP hydrochloride) can be used as the substitute of DTT at low pH value and is also more stable than DTT.


GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.


Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.


Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.


Manufacturer Supply High Quality CAS 3483-12-3 Dl-DithiothreitolManufacturer Supply High Quality CAS 3483-12-3 Dl-DithiothreitolManufacturer Supply High Quality CAS 3483-12-3 Dl-DithiothreitolManufacturer Supply High Quality CAS 3483-12-3 Dl-DithiothreitolManufacturer Supply High Quality CAS 3483-12-3 Dl-Dithiothreitol

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Trading Company
Number of Employees
2
Year of Establishment
2017-08-08