• Linagliptin Intermediate CAS 668270-12-0 Linagliptin
  • Linagliptin Intermediate CAS 668270-12-0 Linagliptin
  • Linagliptin Intermediate CAS 668270-12-0 Linagliptin
  • Linagliptin Intermediate CAS 668270-12-0 Linagliptin
  • Linagliptin Intermediate CAS 668270-12-0 Linagliptin
  • Linagliptin Intermediate CAS 668270-12-0 Linagliptin

Linagliptin Intermediate CAS 668270-12-0 Linagliptin

Powder: Yes
Customized: Non-Customized
Certification: GMP, ISO 9001, USP, BP
Suitable for: Elderly, Children, Adult
State: Solid
Purity: >99%
Samples:
US$ 1/gram 1 gram(Min.Order)
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Basic Info.

Model NO.
TY-02ALI
CAS
668270-12-0
Assay
99%
Shelf
2 Years
Transport Package
25kg/Drum1g, 50g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month

Product Description

Linagliptin Intermediate CAS 668270-12-0 Linagliptin
Linagliptin Intermediate CAS 668270-12-0 Linagliptin

Linagliptin Intermediate CAS 668270-12-0 Linagliptin
 
Product name Linagliptin
CAS 668270-12-0
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Linagliptin Intermediate CAS 668270-12-0 Linagliptin

Product Name:Linagliptin
CAS:668270-12-0
MF:C25H28N8O2
MW:472.54
EINECS:1308068-626-2
Mol File:668270-12-0.mol
Melting point:202 ºC
Boiling point:661.2±65.0 °C(Predicted)
Density 1.39


Linagliptin Intermediate CAS 668270-12-0 Linagliptin

Description

Linagliptin (TrajentaR, TradjentaTM, TrazentaTM, TrayentaTM) is an oral, highly selective inhibitor of dipeptidyl peptidase-4 and is the first agent of its class to be eliminated predominantly via a nonrenal route. Linagliptin is indicated for once daily use for the treatment of adults with type 2 diabetes mellitus.
Treatment of Type 2 diabetesLinagliptin acts to lower blood glucose levels by inhibiting the enzyme DPP-4, thereby preventing the degradation of the incretin hormones (glucagon-like peptide-1 [GLP-1] and glucose-dependent insulinsotropic peptide) and attenuating postprandial glucose excursions. By selectively targeting DPP-4, linagliptin potentially causes a more physiologically based control of glucose-dependent postprandial glucose excursions and of fasting blood glucose, both of which are mediated by effects of glucose on insuline and glucagon secretion. An advantage of linagliptin is that since incretin-stimulated release of insuline is glucose dependent, linagliptin is associated with a low incidence of hypoglycaemia. Moreover, DPP-4 inhibitors have a low potential for drug-drug interactions (with the exception of saxagliptin, which is metabolized by cytochrome P450 [CYP] 3A4/5), are generally well tolerated and have minimal or neutral effects on bodyweight. 
PharmacokineticsLinagliptin shows modest oral bioavailability, and it is rapidly absorbed. UsesA novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
Usesdipeptidypeptidase inhibitor, antidiabetic
Useshighly potent CD26 inhibitor
UsesLabeled Linagliptin, intended for use as an internal standard for the quantification of Linagliptin by GC- or LC-mass spectrometry.



GuangZhou TongYi biochemistry technology Co.,LTD is a company specializing in active pharmaceutical ingredient (API), biology,plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and customer service. With the efforts of all the company's employees, it has established long-term and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.


Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.


Linagliptin Intermediate CAS 668270-12-0 LinagliptinLinagliptin Intermediate CAS 668270-12-0 LinagliptinLinagliptin Intermediate CAS 668270-12-0 LinagliptinLinagliptin Intermediate CAS 668270-12-0 LinagliptinLinagliptin Intermediate CAS 668270-12-0 Linagliptin

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Diamond Member Since 2021

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Trading Company
Number of Employees
2
Year of Establishment
2017-08-08