Human B-raf Gene V600E Mutation Detection Kit-P111H

Studies have shown that B-raf gene mutation exists in a variety of malignant tumors such as non-small cell lung cancer and colorectal cancer. Among them, V600E point mutation on exon 15 is the most common, accounting for more than 90%. This mutation leads to abnormal activation of B-raf protein, which leads to the failure of treatment of patients to receive EGFR-TKI drugs and EGFR monotherapy.

Based on the real-time fluorescent PCR platform, this kit is used to detect B-raf gene V600E mutation by combining alleles specific amplification (ARMS) technology, wild-type gene amplification inhibition technology and multiple PCR technologies. The test result of this kit can assist the clinician in developing drug regimens for patients with non-small cell lung cancer and colorectal cancer.