• High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
  • High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
  • High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
  • High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
  • High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
  • High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema

High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema

CAS No.: 137071-32-0
Formula: C43h68clno11
EINECS: 603-999-7
Type: Pharmaceutical Intermediates
Appearance: Powder
Quality: Refined
Samples:
US$ 100/Piece 1 Piece(Min.Order)
| Request Sample
Customization:
Gold Member Since 2022

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Anhui, China
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Basic Info.

Model NO.
PY202211071348
Colour
White
Transport Package
1kg/Aluminum Bag or 25kg/Drum
Specification
99% min
Trademark
Puya
Origin
China
Production Capacity
5000kilogram/Month

Product Description

High Quality Pimecrolimus CAS 137071-32-0 Treatment Of Skin Diseases Such As Eczema

Product Name:    Pimecrolimus
Synonyms:    ASM 981;Elidel;SDZ-ASM 981;Picrolimus;Pimecrolimus;15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-((1E)-2-((1R,3R,4S)-4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26as)-;15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-(2-(4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S-(3R*(E(1S*,3S*,4R*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26ar*))-;Unii-7kyv510875
CAS:    137071-32-0
MF:    C43H68ClNO11
MW:    810.45
EINECS:    603-999-7
Product Categories:    Inhibitors;Elidel, SDZ-ASM-981;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:    137071-32-0.mol

Pimecrolimus is a topical immunomodulators and is a kind of semi-synthetic products of the Streptomyces-produced ascomycin. It has a greater lipophilicity than tacrolimus with a stronger affinity with the skin. It can effectively and safely control the signs and symptoms of facial seborrheic dermatitis and can quickly relieve the itching symptoms of patients with dermatitis and eczema as well as reduce the lesion area, clear atopic dermatitis (eczema) sign. Therefore, it is an effective treatment method for the treatment of atopic dermatitis (eczema) for both early remission purpose and long-term control purpose.




Pimecrolimus CAS 137071-32-0 of Chemical Properties
Melting point     135-136 °C
Boiling point     866.1±75.0 °C(Predicted)
density     1.19
storage temp.     Keep in dark place,Sealed in dry,2-8°C
solubility     DMSO (Slightly, Sonicated), Chloro form (Slightly), Methan ol (Slightly)
form     Solid
pka    9.97±0.70(Predicted)
color     White to Off-White

Function and Application of Pimecrolimus CAS 137071-32-0
1. Pimercrolimus (21) is the first non-steroid agent for the treatment of mild to moderate atopic dermatitis lunched by Novartis. It selectively blocks the production and release of cytokines from T-cells. These cytokines cause inflammation, redness and itching associated with eczema. Long-term therapy with pimecrolimus (21) was more effective than conventional treatment in reducing the incidence of disease flares and the use of corticosteroids. This drug is also safe and effective in pediatric patients and is approved for use in children as young as two years.
2. Pimecrolimus is a topical immunomodulator, a semi-synthetic product of Streptomyces cysticercus, which is more lipophilic than tacrolimus and has a stronger affinity with the skin. It can effectively and safely control the signs and symptoms of facial seborrheic dermatitis, provide rapid relief of pruritus, reduce the area of lesions and clear the signs of atopic dermatitis (eczema) in patients with dermatitis eczema, and is an effective treatment for early relief and long-term control of atopic dermatitis (eczema).



Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.
Shipping Terms
By Express By Air By Sea
Suitable for under 50kg
Fast:3-4 days
High cost
Door to door service
Easy to pick up the goods
Suitable for more than 50kg
Fast:3-4 days
High cost
Airport to airport
Professional broker needed
Suitable for more than 500kg
Slow:15-30 days
Low cost
Port to port
Professional broker needed

High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
 

High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.
High Quality Pimecrolimus CAS 137071-32-0 Treatment of Skin Diseases Such as Eczema

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.

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Gold Member Since 2022

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Trading Company
Number of Employees
3
Year of Establishment
2023-04-18