| Certification: | RoHS, BRC, ISO, FDA, HACCP |
|---|---|
| Assay Method: | HPLC |
| Application Form: | Injection, Lotion, Suppository, Paste, Tablet, Capsule |
| Application: | Food, Health Care Products, Medicine |
| State: | Powder |
| Appearance: | a Greyish-Yellow to Pale Brown Granular |
| Customization: |
|---|
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[ Product Name ] Diosmin 9:1 Granular
[ CAS ] 520-27-4
[ Appearance ] A greyish-yellow to pale brown granular
[ Active Ingredients ] 9:1
[ Shelf Life ] 2 years if sealed and store away from direct sun light.
[ Introduction ]
The role of diosmin is a vasoprotective agent, mainly to enhance venous tension, improve microcirculation and promote lymphatic return.
[ Main Functions ]
Diosmin is a venous tonic and vasoprotective agent.
1.For the venous system, this product increases the venous tension by prolonging the time that acts on the venous wall to cause contraction.
2.For the microcirculatory system, this product can reduce the permeability of capillaries and enhance their resistance.
3.For the lymphatic system, This product increases the speed of lymphatic drainage and the constriction of lymphatic vessels, improves lymphatic return and reduces edema.
------------------------------ Certificate of Analysis-----------------------------
| Product Name: | Diosmin 9:1 | |||
| Batch No: | 20220403 | Manufacture Date: | 2022.04.03 | |
| Origin: | China | Quantity: | 15kg | |
| Part NO.: | 1.220-023.0 | |||
| Items tested | Specifications | Results | Method | |
| appearance | A greyish-yellow to pale brown Granular | Complies | Visual | |
| Identification | Positive | Complies | HPLC | |
| Solubility |
Practically insoluble in water, soluble in dimethyl sulfoxide, practically insoluble in alcohol it dissolves in dilute solutions of alkali hydroxides. | Complies | Visual | |
| Iodine | ≤ 0.1% | Complies | ||
Substances |
Impurity A(Acetoisovanillone) | ≤1% | Not detected | HPLC |
| Impurity C(Isorhoifolin): | ≤3% | 2.22% | HPLC | |
| Impurity E(Linarin): | ≤3% | 2.16% | HPLC | |
| Impurity F(Diosmitin): | ≤3% | 0.44% | HPLC | |
| Water | ≤6.0% | 4.32% | Eur.Ph.9.0 <2.4.16> | |
| Sulphated Ash | ≤0.2% | 0.06% | Eur.Ph.9.0 <2.5.12> | |
| Solvent Resides | ≤300ppm | ≤300ppm | GC | |
| Particle size | 100% through 40~60 mesh | Complies | USP39 <786> | |
| Heavy metals | ≤20ppm | Complies | ||
| Diosmin: | 81.0%~92.0% | 86.56% | HPLC | |
| Hesperidin: | 9.0%~14.0% | 10.47% | HPLC | |
| Microbiology | ||||
| Total bacteria count | ≤1000CFU/g | 40/g | USP39 <61> | |
| Yeasts and moulds | ≤100CFU/g | 8/g | USP39 <61> | |
| E.Coli | Negative | Negative | USP39 <62> | |
| Salmonella | Negative/10g | Negative/10g | USP39 <62> | |
| Coliforms | ≤10CFU/g | ≤10CFU/g | USP39 <62> | |
| Parking | Packed in Paper-drums and two plastic-bags inside. | |||
| Storage | Store in cool & dry place. Do not freeze. Keep away from strong light and heat | |||
| Shelf life | 2 years when properly stored | |||
| Expiry date | 2022.04.02 | |||
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