| CAS No.: | 137665-91-9 |
|---|---|
| Formula: | C65h90n18o17 |
| EINECS: | 000-000-0 |
| Type: | Cosmetic Peptides |
| Appearance: | Powder |
| Quality: | Top Grade |
| Customization: |
|---|
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Audited Supplier
| Introduction |
| Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells. It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. In mammals, tyrosinase is found only in melanosomes, special compartments within pigment-producing cells. Tyrosinase is not preserved across species and, in fact, can differ drastically in structure even among closely-related species. In humans, differences in the efficiency of tyrosinase determine skin color and are the result of slight modifications in the TYR gene found on chromosome 11 . Decapeptide-12 is approximately 17 times more potent than previous treatments for hyperpigmentation, including hydroquinon/e . Studies in cultured melanocytes over 7 days demonstrated a 27%-43% reduction in melanin content. Decapeptide-12 has undergone multiple animal trials and may eventually be included in commercial products for treating hyperpigmentation. |
| Function |
| Decapeptide-12 is a cosmetic raw material that inhibits melanin formation, lightens pigmentation, reduces pigmentation,and evens and brightens skin tone. It was developed by researchers at Stanford Dermatology and is the only one proven to effectively inhibit Tyrosinase (tyrosinase promotes excessive production of melanin, resulting in uneven pigmentation,dark spots, etc.), a novel peptide activity. Decapeptide-12 is an oligopeptide that is made up of just 12 amino acids. This oligopeptide is known for its anti-tyrosinase activity. Tyrosinase is found in plant and animal tissues and is responsible for catalyzing melanin and other pigments. Decapeptide-12 is being investigated for its possible ability to reduce skin darkening. It's able to interfere with tyrosinase and lighten skin in animal models. Decapeptide-12 reduces the appearance of hyperpigmentation-age spots, sun spots, uneven skin tone and photo damage-without the typical side effects of other brighteners like irritation and redness. Plus, soothing antioxidants like licorice root also ease sensitive skin. |
| Application |
For cosmetic raw materials and R&D Research Lab |
| VC-IP/Ascorbyl Tetraisopalmitate | Tranexamic Acid | 1,4-Dipropionyloxybenzene |
| Alpha Arbutin | Ectoin | Glycyrrhetinic Acid (18-Beta Glycyrrhetinic Acid) |
| Beta Arbutin | Dimethylmethoxy Chromanol | Dimethymethoxyl Chromanyl Palmitate |
| Deoxyarbutin | Alpha Lipoic Acid | Magnesium Ascorbyl Phosphate |
| Kojic Acid | Charcoal Powder(Bamboo) | Sodium Ascorbyl Phosphate |
| Kojic Acid Dipalmitate | Stearyl Glycyrrhetinate | Hydrocotyle Asiatica Extract |
| Ergothioneine | Tetrahydrocurcumin | Potassium 4-Methoxysalicylate |
| Carnosine | Glycolic Acid | Salicylic Acid |
| Undecylenoyl Phenylalanine | Bromelain | Alpha Hydroxy Acid/AHA |
| Caffeic acid | Mequinol | Phytic acid |
| Niacinamide | SymWhite Powder | Snow White |
| Papain | 3-o-ethyl ascorbic acid/VCE | Giga White |
| Monobenzone | Mandelic acid | Glabridin |
| Azelaic Acid | Melatonin | Dipotassium Glycyrrhizinate |
| Ascorbyl Glucoside/AA2G | L-Glutathione Reduced | Procysteine |
| Fullerence C60 | Cetyl Tranexamate HCl/TXC | Hydroxypinacolone reinoate(HPR) |
| Sodium Hyaluronate/Hyaluronic Acid | Beta-Glucan | Sodium Polyglutamate | Inositol |
| Pro-xylane/Hydroxypropyl tetrahydropyrantriol | Collagen | 2-O-β-D-glucosyl-glycerol | Glucosylglycerol |
| Biosaccharide Gum-1 | Ceramide | Orotic Acid Monohydrate | 1,2-Hexanediol |
| Sodium L-pyroglutamate;PCA-Na | D-panthenol | Maltobionic Acid | Lactobionic acid |
| Caprylyl Glycol/1,2-Dihydroxyoctane | DL-panthenol | Allantoin | Polyglutamic Acid |
| Ascorbic Acid (Vitamin C) | Magnesium Ascorbyl Phosphate | Ascorbyl Isostearate | Ascorbyl Glucoside |
| 3-o-Ethyl Ascorbic Acid | Sodium Ascorbyl Phosphate | Ascorbyl Tetraisopalmitate | Ascorbyl Palmitate |
| Apple Polyphenols | Sodium Copper Chlorophyllin | D-Isoascorbic Acid | Ferulic Acid | EGF/Oligopeptide-1 |
| Ascorbyl Palmitate | Resveratrol | Vitamin E | Copper PCA | Vitamin E |
| EUK 134 | Glucosylrutin | Pterostilbene | ZINC PCA | Coenzyme Q10 |
| Vanillyl butyl ether | Menthol Crystal | Menthyl lactate | Menthone 1,2-glycerol ketal |
| Capsaicin | WS-23 | Camphor | WS-3 |
| Q: What types of cosmetic raw materials do you supply? |
| We supply a wide range of cosmetic raw materials, including but not limited to whitening agents, moisturizing agents, antioxidation, emollients, surfactants, preservatives, pigments, and active ingredients to meet diverse formulation needs. |
| Q: How can I place an order for cosmetic ingredients? |
| To place an order, simply browse our product catalog, select the desired items, and follow the online checkout process. If you have specific requirements or need assistance, our customer service team is ready to help. |
| Q: What is the minimum order quantity for your cosmetic raw materials? |
| The minimum order quantity varies by product. You can find this information on the product pages or contact our sales team for specific details. Usually MOQ is from 1kg. |
| Q: Can I request a sample of a specific cosmetic ingredient before placing a bulk order? |
| Yes, we offer sample sizes for most of our products. You can request samples through our website, and our team will assist you in choosing the right products for your needs. |
| Q: What quality standards do your cosmetic raw materials adhere to? |
| Our cosmetic raw materials adhere to industry-standard quality and safety regulations. We ensure compliance with relevant standards and provide documentation, such as Certificates of Analysis, upon request. |
| Q: What payment methods do you accept for cosmetic ingredient purchases? |
| We accept various payment methods, including credit cards, bank transfers, and other secure online payment options. Details are available during the checkout process. |
| Q: How do you ensure the timely delivery of cosmetic raw materials? |
| We work with reliable shipping partners to ensure timely and secure delivery of your orders. You can track your shipment through tracking website and our customer service team is available to assist with any delivery-related inquiries. |
| Q: Do you provide technical support or documentation for the proper usage of your cosmetic raw materials? |
| Absolutely. We offer technical support and provide comprehensive documentation, including usage guidelines and formulation recommendations. Our team is available to address any technical inquiries you may have. |
Suppliers with verified business licenses
Audited Supplier 
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