Chemical Raw Material Intermediates Powder Alendronate Sodium CAS 121268-17-5

Description:
Alendronate sodium is a bisphosphonate drug used for osteoporosis and several other bone diseases. And it used for prophylaxis and in treatment of female and male osteoporosis. It has been used for prevention and treatment of corticosteroid-associated osteoporosis together with supplements of calcium and vitamin D, and used for paget's disease.
Function:
1. This product is third-generation hydrocarbon phosphate bone resorption inhibitors, mainly deposited in bone resorption area of osteoclasts, the osteoclast is exposure to the surface than osteoblast surface in the large 10-fold. Drugs and bone hydroxyapatite in combination, do not interfere with osteoclast aggregation and adhesion, but inhibited the activity of osteoclasts and the release of H capacity.
2. On the other hand, the product acts on osteoclasts and inhibit osteoclast activating factor produced, so that the number of osteoclast activity decreased. Because osteoclast activity is inhibited, so that lower bone turnover, bone reconstruction reduce the number of points, and the formation of bone in the reconstruction point is greater than bone resorption and prevent osteolysis, the bone density increase.
3. This product can be absorbed orally, the role of durable, long-term application. No inhibition of bone mineralization.