Cas:64485-93-4 Cefotaxime sodium
| product name |
Cefotaxime sodium |
| cas number |
64485-93-4 |
| apperance |
white powder |
| Density |
1.8 g/cm3 |
| MF |
C16H16N5NaO7S2 |
| MW |
477.447 |
Cefotaxime sodium (Cefotaxime sodium) is a third-generation semi-synthetic cephalosporin, which is not as effective as cefazolin on gram-positive bacteria. Enterococcus is resistant to this product, is ineffective against penicillin-resistant pneumococcus, and is gram-negative. Bacteria has strong bactericidal activity. It has stronger antibacterial effect on Escherichia coli, influenza bacillus, pneumoniae bacillus, Proteus mirabilis and Salmonella than cefoperazone, weak or resistant to Bacteroides fragilis, aeruginosa, cloacae Enterobacteria are not sensitive to this product.
Cefotaxime is widely distributed in various tissues and body fluids throughout the body. The drug concentration in normal cerebrospinal fluid is very low; after applying this product in patients with meningitis, the effective concentration in cerebrospinal fluid can be reached. Effective concentrations can also be reached in bronchial secretions, middle ear discharge, pleural effusion, empyema pus, ascites, gallbladder wall, bile, and bone tissue: this product can enter the fetal blood circulation through the placental barrier, and a small amount is also acceptable Into the breast milk.
It is used for infections of the respiratory tract, urinary tract, bones and joints, skin and soft tissues, abdominal cavity, biliary tract, digestive tract, facial features, genitals, etc. caused by sensitive bacteria. It is also effective for infections caused by burns and trauma, as well as sepsis and central infections.
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