CAS 37942-07-7 3,5-di-tert-Butyl Salicylaldehyde

3,5-Di-tert-butylsalicylaldehyde, also known as 3,5-Di-tert-butyl-2-hydroxybenzaldehyde, is an organic intermediate, which can be prepared from 2, 4-di-tert-butylphenol through one-step reaction. It has been reported that it can be used to prepare dimethyl ethylenediamine tert-butylphenol and (S,S)-salenCo (II) catalyst.

3,5-Di-tert-butylsalicylaldehyde is used in the synthesis of Mn(III)-salen complex and its diamino precursor 5,6-diamino-5,6-dideoxy-1,2-O-isopropylidene-3-O-methyl-β-L-idofuranose, chiral Schiff base ligand for an enantioselective copper-catalyzed addition of phenyl acetylene to imines, chiral oxazolidine ligand for the enantioselective addition of diethyl zinc to aldehydes and tin Schiff base complexes with histidine analogues. 

3,5-Di-tert-butylsalicylaldehyde is a salicylaldehyde derivative with antibacterial activity used in the preparation nickel complexes. 3,5-Di-tert-butylsalicylaldehyde is structurally related to 3,5-di-t-butylcatechol (DTCAT) but is not as potent an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).
1. Steric Hindrance: 3,5-Di-tert-butylsalicylaldehyde contains two bulky tert-butyl groups attached to the phenolic ring. This steric hindrance restricts molecular interactions, making it challenging for other molecules or metal ions to access specific reactive sites.

2. Antibacterial Activity: The compound exhibits antibacterial properties, which can be beneficial in various applications, such as antimicrobial coatings or additives in certain products.

3. Coordination Chemistry: 3,5-Di-tert-butylsalicylaldehyde can serve as a ligand in coordination complexes with various metal ions. Its steric hindrance influences the geometry and stability of the resulting metal complexes.

4. Chirality: Due to its steric configuration, 3,5-Di-tert-butylsalicylaldehyde can serve as a chiral building block for the synthesis of chiral catalysts and ligands. This property is significant in asymmetric catalysis and organic synthesis.

5. Electronic and Photophysical Properties: The tert-butyl groups' presence can influence the electronic and photophysical properties of 3,5-Di-tert-butylsalicylaldehyde and its derived compounds, making them interesting for optoelectronic and materials research.

6. Applications in Chemical Research: 3,5-Di-tert-butylsalicylaldehyde is widely used in chemical research and the development of new materials, particularly in the synthesis of complex organic molecules.

7. Precursor in Nickel Complexes: The compound is often employed in the preparation of nickel complexes, which can have diverse applications in catalysis and materials science.

8. Structural Similarity: While structurally related to 3,5-di-t-butylcatechol (DTCAT), 3,5-Di-tert-butylsalicylaldehyde does not possess the same potent activating properties of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).
1. Coordination Chemistry
3,5-Di-tert-butylsalicylaldehyde can act as a ligand in coordination complexes with different metal ions. These metal complexes find use as catalysts in organic transformations and materials synthesis.

2. Chiral Building Block
Its chiral nature makes 3,5-Di-tert-butylsalicylaldehyde a valuable building block for the synthesis of chiral catalysts and ligands. These compounds play a crucial role in asymmetric catalysis, which is essential for the production of enantiomerically pure compounds.

3. Antibacterial Agents
3,5-Di-tert-butylsalicylaldehyde's antibacterial activity makes it useful in formulating antimicrobial coatings, additives, or treatments for various applications, including medical devices, paints, and coatings.

4. Organic Synthesis
The compound is utilized in chemical research and organic synthesis as a precursor for the preparation of complex organic molecules and pharmaceutical intermediates.

5. Nickel Complexes
3,5-Di-tert-butylsalicylaldehyde is employed in the synthesis of nickel complexes, which have applications in catalysis and materials science.

6. Materials Science
Its unique electronic and photophysical properties make it interesting for research in the development of optoelectronic materials and related devices.

7. Ligands in Metal Coordination
As a ligand, 3,5-Di-tert-butylsalicylaldehyde influences the coordination geometry and stability of metal complexes, making it important in the design and synthesis of novel materials.   

 

Storage: Keep in dark place,Sealed in dry,Room Temperature.

Package: 50kg/bag or as per your particular request.

Beijing Entrepreneur Science & Trading Co., Ltd. was established in the year 2001. We are focused on import and export business of high-quality specialty chemicals. Since its establishment, relying on diligent efforts, spirit of enterprising and professional services, the company has established extensive cooperation with world-famous chemical manufacturers and gained a good reputation in China chemical industry.

We have stable distribution cooperation with world leading suppliers from America, Europe, Japan and Taiwan. We are distributors of Ames Advantage Material, Novamet, Lanxess, Momentive, Potters, Rhodia, Roquette, Oerlikon Metco, Inovyn, KJ Chemical, Tokuyama, Mitsubishi Chemical, Chang Chun Group, etc.
 
Our products selling in China include Conductive Powder, Thermal Conductive Powder, Microwave Absorbing Powder, Acrylamide Functional Monomer and Special UV Monomer, Special Epoxy Resin, Mercaptan Curing Agent, Silane, Fumed Silica and Precipitated Silica, PVC Paste Resin, PVA, Carbon Black, Modified Starch, Photocatalyst, Formaldehyde Capture agent, Root Blocking Agent, Platinum Catalyst, Vinyl Silicone Oil, Surfactant, etc.

In 2014, the company entered the chemical export business. Based on our understanding of China chemical market, we select most qualified suppliers. We are able to source raw materials directly from factories. Most of our partners are the largest factory in China with over 20 years history. They have huge annual outputs, and hold ISO9001, ISO14001, GMP, KOSHER, HALAL, FDA, GSP, etc. certificates.
 
Our export products include Conductive Powder, Thermal Conductive Powder, Plant Extract, Inorganic Powder, Plasticizer, PVC Paste Resin, Silane, Flavors and Fragrances, Salen Catalysts and Ligands, Organic Intermediates, Pharmaceutical Intermediates. 
We are proud to serve industries such as coating, ink, sealant, industrial, cosmetics, conductive powder, thermal conductive powder, pharmaceutical, flavor & fragrance, aroma, as well as many others. 
 
We will support our customers in a continuous way in the following:
1. Timely feedback to inquiry within 24 hours
2. Pre-sales consultancy 
3. Supply samples 
4. Competitive price
5. Good packaging
6. Timely delivery
7. Small order is available
8. Good after sales services
9. Provide TDS, COA, commercial invoice, packing list and certificate of origin. Special requirements also could be discussed and met. 
Can I request samples?
Yes, absolutely! We offer free samples of specified quantities. You only need to cover the freight charges.
Which documents are provided?
We provide essential documents such as Certificate of Analysis (COA), Technical Data Sheet (TDS), Material Safety Data Sheet (MSDS), and more upon request.
What is your Minimum Order Quantity (MOQ)?
Typically, our MOQ is one standard package. However, we understand the importance of testing before committing to a mass order, so we offer free samples for your evaluation.
How do you ensure the quality of your products?
We prioritize quality assurance through several measures:
1. Expert Staff: Our team comprises professionals with extensive experience in chemical products or related fields. They undergo comprehensive training before providing any quotations.
2. Sample Availability: We offer free samples or pre-shipment samples for new collaborations, ensuring that our commercial products match the specifications provided to customers.
3. Third-Party Inspection: Upon request, we can arrange Third-Party Inspections, such as SGS, to further validate the quality of our products before shipping.
How do I make payments?
Once you receive the Proforma Invoice (PI) along with our product specifications, you can proceed with payment. We accept various payment methods including Telegraphic Transfer (T/T), Letter of Credit (LC), and more.
What is your after-sales service like?
At Beijing Entrepreneur Science & Trading Co., Ltd., we prioritize fostering long-term relationships with all our customers. For every order, we ensure transparency and commitment by signing a legally binding sales contract. Should you have any doubts or concerns regarding our products or services, please do not hesitate to contact us. Your satisfaction and trust are our top priorities.
Can I use my own label or packaging?
Absolutely. If required, we can use labels or packaging according to your specifications and preferences. Your branding and packaging needs are important to us, and we'll ensure they are met to your satisfaction.