Botanical Pesticides Cnidium Extract 10%-98% Osthole Cnidium Monnieri (L.) Cuss Pharmaceutical Grade

Certification:	ISO, FDA
Assay Method:	HPLC, UV, Tlc
Application Form:	Tablet, Capsule
Application:	Food, Health Care Products, Medicine
State:	Brownish Yellow Powder
Extract Source:	Fruit

Samples:	US$ 0/g 1 g(Min.Order) \| Request Sample

Customization:	Available \| Customized Request

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Company Info.

Basic Info.

Payment

T/T in Advance

Shelf Life

24 Months

Delivery Time

3-5 Working Days

Free Sample

Available

Transport Package

25kg/Cardboard Drum I. D. 42cm X H. 52cm

Specification

10%-98% Osthole

Trademark

Shanghai, China

Origin

China

HS Code

13021990

Production Capacity

20 Ton/Month

Product Description

Product Profile
Cnidium monnieri, also known as wild fennel, wild carrot seed, snake rice, snake chestnut, etc., is the dried and mature fruit of the Apiaceae plant Cnidium monnieri. Snake bed is an annual herbaceous plant that likes warm and humid environments. It is not afraid of severe cold and drought and has wide adaptability. It is distributed in East China, Central South and other regions of China.

Effects and applications of Cnidium monnieri
1.For external use
Antibacterial: Oosthole has inhibitory effects on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and can also reduce the pathogenicity of residual strains of Staphylococcus aureus. It can be used in conjunction with matrine, etc. to treat trichomonal vaginitis, eczema, psoriasis, etc.

2. Oral administration
2.1 Anti-inflammation: Oosthole has an inhibitory effect on Staphylococcus aureus and has a good effect on bacterial inflammation. Oosthole and baicalin are used together to synergistically treat pneumonia caused by Staphylococcus aureus.

2.2 Anti-cancer: osthole can inhibit tumor growth in mouse liver cancer models, induce apoptosis of liver cancer cells through multiple targets and multiple pathways, and enhance the anti-tumor immune response in liver cancer mice; osthole can also kill Nasopharyngeal cancer cells, lung cancer cells and cervical cancer cells have inhibitory effects on the growth of various tumor cells. Can be used to aid in the fight against cancer.

2.3 Anti-osteoporosis: Oosthole can significantly promote the proliferation and differentiation of bone marrow mesenchymal stem cells and osteoblasts, and significantly increase the expression levels of osteocalcin and alkaline phosphatase, thereby promoting bone formation and increasing bone mineral content. and bone strength. The effect of osthole on promoting osteoblast proliferation and differentiation is related to the concentration, and the concentration is between 5*10-5M-5*10-4M. In addition, osthole and puerarin can be used together to treat bone dysplasia and osteoporosis.

2.4 Effect on the endocrine system: osthole can promote the synthesis and secretion of androgens in Leydig cells of mice by regulating the gene transcription of enzymes and their cell membrane and cytoplasm-related receptors in the androgen synthesis process of Leydig cells in mice; It can also increase the levels of testosterone, follicle-stimulating hormone, and luteinizing hormone in the serum, and has androgen-like and gonadotropin-like effects; and osthole at 40-80 μg/mL can effectively alleviate the oxidation caused by H2O2 in ovarian tissue. Stress damage, protect the function of ovarian tissue, and enhance the antioxidant capacity of ovarian tissue.

3.Biological pesticides
Low-content osthole can be used as a botanical insecticide, stored grain protective agent, etc. As a pesticide, osthole has passed organic certification and can be used in organic product bases. 1% osthole aqueous emulsion has special effects on powdery mildew on melons, strawberries, and flowers (the control efficiency is about 95%). It also has a concurrent control effect on vegetable downy mildew and aphids. 4% osthole powder has good control effect on corn weevil, millet beetle (dù) and Tribolium castaneum adults. Compared with other plant-derived pesticides, osthole has the advantages of high efficiency and low toxicity.

Certificates of Analysis

Product Name:	Cnidium Extract		Latin Name:		Cnidium monnieri (L.) Cuss
Part used:	Fruit		Country of origin		China

Item		Specification		Result
Aaasy		10% Osthole		HPLC
Physical & Chemical
Appearance		Brownish yellow powder		Conforms
Odor & Taste		Characteristic		Characteristic
Particle Size		90% through 80 mesh		Conforms
Loss on Drying		≤5.0%		1.32%
Ash		≤5.0%		2.11%
Heavy metals
As		≤2ppm		Conforms
Lead (Pb)		≤2ppm		Conforms
Cadmium(Cd)		≤1ppm		Conforms
Microbiological Test
Total Plate Count		NMT 1000cfu/g		Conforms
Total Yeast & Mold		NMT 100cfu/g		Conforms
E.Coli		Negative		Negative
Salmonella		Negative		Negative
Pesticide Residue		Negative		Negative