Pharmaceutical Intermediate CAS 59198-70-8 Diflucortolone Valerate

Description

English alias Afussona

Nerisone

Nerisona

Neriforte

59198-70-8

Nerisone Forte

Youtolon[Tatsumi]

DIFLUCORTOLONE VALERATE

Diflucortolone valerate

Diflucortolone 21-valerate

Diflucortolone valerate (JAN)

6a,9-difluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-valerate

(6alpha,11beta,16alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl valerate

Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6 α, eleven β, sixteen α)-

(6alpha,11beta,16alpha)-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pentanoate

pentanoic acid, (6alpha,11beta,16alpha)-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl ester

CAS 59198-70-8

EINECS 261-655-8

Chemical formula C27H36F2O5

Molecular weight 478.57

InChI InChI=1/C27H36F2O5/c1-5-6-7-23(33)34-14-21(31)24-15(2)10-17-18-12-20(28)19-11-16(30)8-9-26(19,4)27(18,29)22(32)13-25(17,24)3/h8-9,11,15,17-18,20,22,24,32H,5-7,10,12-14H2,1-4H3/t15-,17+,18+,20+,22+,24-,25+,26+,27+/m1/s1

Density 1.1227 (estimate)

Melting point 220 ° C

Boiling point 578.5 ± 50.0 ° C (Predicted)

Specific rotation D22+100.8 ° (dioxane)

Flash point 303.7 ° C

Steam pressure 8.58E-16mmHg at 25 ° C

Solubility Chloroform (Slightly), Dioxane (Slightly), Methanol (Slightly)

Refractive index 1.538

Acidity coefficient 12.89 ± 0.70 (Predicted)

Storage condition - 20 ° C Freezer, Under iner atmosphere

Appearance Solid

Color White to Off-White

Product use Difluctolone valerate is a powerful corticosteroid, which can be used for the research of various skin diseases.