| CAS No.: | 30123-17-2 |
|---|---|
| Formula: | C21h24cln2nao4s |
| EINECS: | 250-059-3 |
| Environmental Protection: | Yes |
| Certification: | ISO |
| Color: | White |
| Customization: |
|---|
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Audited Supplier | Product Name | Tianeptine sodium salt |
| CAS | 30123-17-2 |
| Assay | 99% |
| Appearance | White or off-white crystalline powder |
| MF | C21H24ClN2NaO4S |
| MW | 458.93 |
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.
Specification
| ITEM | SPECIFICATION | RESULT |
| Appearance | White to yellowish powder,very hygroscopic. |
Off-white powder,very hygroscopic. |
| Solubility | Freetly soluble In water and methanol and dichloromethane | Complies |
| Identification | By HNMR, To match with working standard | Complies |
| It gives reaction of sodium | Complies | |
| Impurities A | ≤0.1% | Not detected |
| Related compounds | Any impurity ≤0.1% | 0.1% |
| Total impurities ≤0.4% | 0.1% | |
| Residual Solvents | Acetidin≤ 0.5% | Not detected |
| Dichloromethane≤ 0.06% | Not detected | |
| Methanol≤ 0.3% | Not detected | |
| Acetone ≤ 0.5% | Not detected | |
| Acetonitrile≤0.041% | Not detected | |
| Ethanol≤0.5% | Not detected | |
| N, N-dimethylformamide≤0.088% | Not detected | |
| Water | ≤ 5.0% | 1.9% |
| Assay | 99.0%-101.0%(On anhydrous basis) | 99.9% |
| Conclusion | The product meet the testing requirements | |
Application
Tianeptine is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
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Q5: How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will send you free goods for replacement or refund your loss
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