High quality MO TS-c / mo ts-c 10mg peptide cas 1627580-64-6 with best price
Name: MO TS-c
CAS No. : 1627580-64-6
Molecular formula: C101H152N28O22S2
Molecular weight : 2174.6
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of additional sORFs in the mtDNA. Here we report a sORF within the mitochondrial 12S rRNA encoding a 16-amino-acid peptide named MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) that regulates sensitivity and metabolic homeostasis. Its primary target organ appears to be the skeletal muscle, and its cellular actions inhibit the folate cycle and its tethered de novo purine biosynthesis, MO TS-c treatment in mice prevented age-dependent and high-fat-diet-induced resistance, as well as diet-induced obesity. These results suggest that mitochondria may actively regulate metabolic homeostasis at the cellular and organismal level via peptides encoded within their genome.
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Q1: How to confirm the Product Quality before placing orders?
A. Offering you our products specification standard (tested by HPLC, UV, GC and TLC etc.)
B. Free samples could be sent to check the product quality before ordering.
C. If you have special requirement on the product, we may customize it according to your requirement until to your approval.
Q2: Samples & MOQ
A. We could provide some free samples, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
B. For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 1kg.
Q3: How about delivery?
A: Delivery lead time: within 3 days when get the payment.
B. Samples: please expect 5-7 days by FedEx,EMS, UPS,TNT.