Huizhou, Guangdong, China
Member Since: 2012
Business Type: Manufacturer/Factory
There have been few studies of the effect of alginate dressings on the processes of wound healing.
The healing of cutaneous ulcers requires the development of a vascularized granular tissue bed, filling of large tissue defects by dermal regeneration, and the restoration of a continuous epidermal keratinocyte layer. These processes were modeled in vitro in one study, utilizing human dermal fibroblast, microvascular endothelial cell (HMEC), and keratinocyte cultures to examine the effect of calcium alginate on the proliferation and motility of these cultures, and the formation of capillarylike structures by HMEC.
In the study, the calcium alginate increased the proliferation of fibroblasts but decreased the proliferation of HMEC and keratinocytes. In contrast, the calcium alginate decreased fibroblast motility but had no effect on keratinocyte motility. There was no significant effect of calcium alginate on the formation of capillarylike structures by HMEC. The effects of calcium alginate on cell proliferation and migration may have been mediated by released calcium ions.
These results suggest that the calcium alginate tested may improve some cellular aspects of normal wound healing, but not others.
|Alginate Dressing||50 x 50 mm||10pcs/box, 60boxes/carton|
|Alginate Dressing||100 x 100 mm||10pcs/box, 60boxes/carton|
|Alginate Dressing||120 x 100 mm||10pcs/box, 60boxes/carton|
|Alginate Dressing||300 x 20 mm||10pcs/box, 60boxes/carton|
|Alginate Dressing (Rope)||30.5mm/ 2g||10pcs/box, 60boxes/carton|