Pharmaceutical Chemical Phenolphthalein CAS 77-09-8 for Laxatives and Antidiarrheal Medicines
Phenolphthalein is a chemical that is commonly used as a colorimetric pH indicator. Phenolphthalein has been observed to turn orange at pH <0, clear between pH 0-8.2, fuchsia between pH 8.2-12, and clear again at a pH above 12. Phenolphthalein has been postulated that the mutagenic effects of Phenolphthalein at high doses can be attributed the enhancement intracellular free oxygen radicals. Phenolphthalein has also been observed to induce mitotic abnormalities and micronuclei with kinetochores in vitro. In Syrian hamster embryos treated with 10-40 μM of Phenolpthalein a significant number of chromosomal aberrations occurred at the hprt locus. On human breast cancer cells Phenolphthalein has been observed to have weak estrogenic effects.
Item |
Specifications |
Characteristics |
A white or almost white powder, practically insoluble in water, soluble in alcohol. |
Melting Point |
It melts at about 260ºC |
Identification |
A:Positive B:Positive |
Appearance of solution |
The solution is clear and not more intensely coloured than reference solution Y7 |
Related substances |
Less than 0.5% |
Heavy metals |
Not more than0.001% |
Acidity or alkalinity |
Complies |
Chlorides |
Not more than 0.01% |
Sulphates |
Not more than 0.02% |
Loss on drying |
Not more than 0.5% |
Sulphated ash |
Not more than 0.1% |
Assay |
98.0%-101.0%(C2OHi4O4) |
Microorganism |
TPC<1000cfu/g |
Y and M <100cfu/g |
E-coli - absent |
Staphylococcus Aureus-Absent |
Pseudomonas Aeruginosa-Absent |
Albicans Saccharomyces-Absent |
Q1:Can I get some samples?
A: Yes, we can supply the free sample,customer only need bear the shipping cost.
Q2:How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T,Western Union or Paypal or secure payment.
Q3: How about delivery lead time?
A: About 7-10 days after payment confirmed.(Chinese holiday not included).
Q4:Is there any discount?
A: Different quantity has different discount.
Q5: How to ship it?
A: For small order, we would send by express such as Fedex, DHL, etc. For large order, we would send by air or sea.