Function: | Vitamins and Minerals Deficiency Drug |
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Grade Standard: | Medicine Grade |
Type: | Chemical Reagent |
State: | Powder |
Volatile: | Not Volatile |
CAS: | 154-17-6 |
Samples: |
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Customization: |
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Product name |
2-Deoxy-D-glucose |
CAS |
154-17-6 |
Synonyms |
2-deoxy-d-arabino-hexos;2-deoxy-d-glucos;2-deoxy-d-mannose;2-deoxy-glucos; 2-desoxy-d-glucose;2-dg;d-2-deoxyglucose;2-DG |
Molecular formula |
C6H12O5 |
Molecular weight |
164.16 |
Purity |
99% |
Appearance |
White powder |
EINECS number |
205-823-0 |
Application |
Pharmaceutical Raw Materials;chiral;Biochemistry;Deoxysugars;Glucose;Sugars; Carbohydrates & Derivatives |
2-Deoxy-D-glucose is an apoptosis inhibitor that has been shown to be taken up by glial cells incubated with insuli. Studies indicate that this compound has the potential to suppress hypoxia in murine retinal tissue. Additionally, 2-Deoxy-D-glucose has been noted to be a glycolytic inhibitor via indirect inhibition of hexokinase (HXK) which results in endoplasmic reticulum stress.
Other experiments suggest that this agent upregulates autophagy and lowers ATP levels in certain cancer cell lines. 2-Deoxy-D-glucose is an activator and an inhibitor of GPI
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