• USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
  • USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
  • USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
  • USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
  • USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
  • USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine

USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine

Function: Vitamins and Minerals Deficiency Drug
Grade Standard: Medicine Grade
Type: Chemical Reagent
State: Powder
Volatile: Not Volatile
Standard: Ep USP
Samples:
US$ 190/kg 1 kg(Min.Order)
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Customization:
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Anhui, China
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Basic Info.

Model NO.
py0070
MOQ
1kg
Package
Carton
Shipping
FedEx
Transport Package
25kg/Drum
Specification
99%
Trademark
puya
Origin
China
Production Capacity
5ton/Month

Product Description

CAS 599-79-1 Sulfasalazine
Product name Sulfasalazine
CAS NO. 599-79-1
Molecular Formula C18H14N4O5S
EINECS: 209-974-3
MW 398.39
Appearance Dark yellow to brownish yellow powder
Purity 99%

1. Sulfasalazine is an antiinflammatory agent that inhibits GSH-H-transferase. Sulfasalazine largely inhibits NF-κB activation and induces apoptosis in T-lymphocytes.
2. The compound also engages neutrophil apoptosis that can be abrogated by Tyr-K inhibitors, PKA inhibitors, or antioxidants. Sulfasalazine is shown to inhibit basic fibroblast growth factor-induced endothelial cell chemotaxis.
USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
USP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
Specification
 
Items Standards Results
Appearance Dark yellow to brownish yellow powder Complies
Identification By HPLC Complies
Melting Point 120ºC~130ºC 126ºC
Loss on Drying 1.00% 0.21%
Heavy Metals  10ppm Complies
Sulfated Ash  0.10% 0.03%
Content 17.5%~19.5% 19.3%
Arsenic Content  0.1ppm 0.09ppm
Lead VContent  3.0ppm 0.50ppm
 Content  0.1ppm 0.10ppm
Content  0.1ppm 0.10ppm
Microbiological Test Coliforms:Negative Negative
SalmonellaNegative Complies
Total plate count1000 CFU/g Pass
Yeast&Mold: 50 CFU/g Pass
Related Substances Impurity A: 0.30% 0.18%
Other unknown impurity0.10% 0.07%
Total Impurities0.50% 0.42%
Assay  98.0% 99.50%
Reference Standard USP Standard
Conclusion The product complied to USP standard.
Storage Preserve in tight,light-resistant containers in a cool place

Function
Sulfasalazine is a prodrug of the anti-inflammatory agent 5-aminosalicylic acid that is covalently linked to the antibiotic
sulfapyri-dine by an azo bond. This bond is rapidly cleaved by bacteria in the terminal ileum and colon, thus releasing the active
anti-inflammatory component. It has long been used in treatment of inflammatory bowel disease and rheumatoid arthritis because of
its ability to induce T lymphocyte apoptosis, modulate inflammatory mediators from both cyclooxygenase/5-lipoxygenase pathways and
NF-κB signaling pathways, attenuate transcription of proinflammatory cytokines, and activate PPAR

Application
1.Sulfasalazine Applied in pharmaceutical field
2.Sulfasalazine Applied in health product field

USP Grade Pharmaceutical Raw Materials CAS 599-79-1 SulfasalazineUSP Grade Pharmaceutical Raw Materials CAS 599-79-1 Sulfasalazine
 

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Gold Member Since 2022

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Trading Company
Number of Employees
3
Year of Establishment
2023-04-18